pentobarbital will lessen the level or impact of lefamulin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Stay clear of coadministration of lefamulin with robust or average CYP3A inducers unless the profit outweighs hazards. Observe for decreased efficacy.
Exercise caution when administered to individuals with acute or Persistent ache; could cause paradoxical pleasure or important signs and symptoms might be masked
pentobarbital will lessen the level or influence of eucalyptus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.
pentobarbital will minimize the level or influence of quetiapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Keep an eye on Closely (one)pentobarbital will reduce the extent or influence of hydrocodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Caution when discontinuing CYP3A4 inducers which can be coadministered with hydrocodone; plasma concentrations of hydrocodone may increase and may lead to possibly lethal respiratory depressionSerious - Use Substitute (1)hydrocodone, pentobarbital.
pentobarbital will decrease the extent or outcome of triamcinolone acetonide injectable suspension by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
benzhydrocodone/acetaminophen and pentobarbital both of those boost sedation. Keep away from or Use Alternate Drug. Restrict use more info to people for whom alternate procedure possibilities are insufficient
If this drug is made use of for the duration of pregnancy, or If your affected individual results in being Expecting whilst taking this drug, the client ought to be apprised from the prospective hazard for the fetus
pentobarbital will lessen the level or influence of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with powerful CYP3A4 inducers may result in decreased serum concentrations and loss of antimalarial efficacy
pentobarbital will lower the extent or effect of conjugated estrogens, vaginal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will lower the level or outcome of tamoxifen by impacting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Monitor.
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pentobarbital will lower the extent or impact of lopinavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lower the level or effect of efavirenz by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.